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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCRS1 All Species: 28.79
Human Site: S87 Identified Species: 52.78
UniProt: Q96EZ8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96EZ8 NP_001012300.1 462 51803 S87 E P G R C S G S E P S S S E K
Chimpanzee Pan troglodytes XP_509047 513 57528 S138 E P G R C S G S E P S S S E K
Rhesus Macaque Macaca mulatta XP_001109790 462 51406 S87 E P G R C S G S E P S S S E K
Dog Lupus familis XP_850537 462 51831 S87 E P G R C S G S E P S S S E K
Cat Felis silvestris
Mouse Mus musculus Q99L90 462 51674 S87 E S G R C S G S E P S S S E K
Rat Rattus norvegicus NP_001013124 462 51804 S87 E S G R C S G S E P S S S E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512056 254 28409
Chicken Gallus gallus XP_001232507 447 50517 S93 V S T P V A P S P V P A P S L
Frog Xenopus laevis NP_001080873 453 50959 V88 S S E K K K Q V C K A I S T P
Zebra Danio Brachydanio rerio NP_998438 472 53117 S95 E P I R C P G S D L M S S D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647852 578 63519 S132 S S R P R T T S Q N Y P A L V
Honey Bee Apis mellifera XP_624688 469 53205 Q89 P I E S T V P Q Q N A S S P I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797067 874 96141 S403 L T L Q S T P S T T T Q H H S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 94.1 99.1 N.A. 98.2 98.4 N.A. 45 85.2 82 75.4 N.A. 44.6 51.5 N.A. 33.9
Protein Similarity: 100 90 94.5 99.3 N.A. 98.4 98.6 N.A. 48 90.9 90 86.2 N.A. 59 69.5 N.A. 43.1
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 6.6 6.6 60 N.A. 6.6 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 20 20 73.3 N.A. 26.6 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 16 8 8 0 0 % A
% Cys: 0 0 0 0 54 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % D
% Glu: 54 0 16 0 0 0 0 0 47 0 0 0 0 47 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 47 0 0 0 54 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 0 0 8 0 0 8 % I
% Lys: 0 0 0 8 8 8 0 0 0 8 0 0 0 0 54 % K
% Leu: 8 0 8 0 0 0 0 0 0 8 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % N
% Pro: 8 39 0 16 0 8 24 0 8 47 8 8 8 8 8 % P
% Gln: 0 0 0 8 0 0 8 8 16 0 0 8 0 0 0 % Q
% Arg: 0 0 8 54 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 39 0 8 8 47 0 77 0 0 47 62 70 8 8 % S
% Thr: 0 8 8 0 8 16 8 0 8 8 8 0 0 8 0 % T
% Val: 8 0 0 0 8 8 0 8 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _